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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage

Fig. 9

Effect of DPM on ICH-induced brain damage in a mouse model of autologous blood ICH. a T2-weighted turbo spin echo magnetic resonance images after 24 h of false ICH operation (sham), 0.9% saline (vehicle), free dauricine (DRC), empty micelles (PM) or dauricine-loaded micelles (DPM). The areas demarcated with dash lines contain a bright rim surrounding the hematoma due to edema formation and/or extruded serum from the injected blood. b Representative sections of brain tissue stained with hematoxylin-eosin. Magnification, ×100. c Representative sections of brain tissue stained with cresyl violet. Magnification, ×20. d Representative sections of brain tissue stained with Perl’s stain to detect iron. Magnification, ×200

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Journal of Nanobiotechnology

ISSN: 1477-3155

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