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Table 1 Keyes’ scores for assessment the efficiency of different treatments on the development of dental caries in rats

From: Farnesal-loaded pH-sensitive polymeric micelles provided effective prevention and treatment on dental caries

Treatment

Smooth-surface caries

Sulcal-surface caries

E

E

Ds

Dm

Dx

Distilled water

10.3 (2.1)a

36.5 (4.6)a

21.8 (2.3)a

8.8 (1.3)a

0.7 (0.8)a

15% Ethanol

9.6 (2.0)a

35.3 (1.7)ac

21.5 (3.7)a

8.9 (2.4)a

0.5 (0.5)a

Farnesol

7.9 (2.6)ac

33.4 (1.9)ac

20.8 (3.4)a

9.4 (2.6)a

0.5 (0.7)a

Farnesal

6.9 (2.2)ac

32.2 (1.9)acd

17.2 (1.6)ac

7.6 (1.7)a

n.d.

Chlorhexidine

2.2 (1.2)bd

25 (2.7)b

12.6 (2.7)bc

3.3 (1.4)bcde

n.d.

Blank PMs

9.9 (2.4)a

34.7 (2.2)ac

21.3 (5.2)a

7.7 (2.4)a

0.4 (0.4)a

Far-PMs

5.1 (2.2)bc

32.7 (2.7)ac

17.1 (0.5)ac

6.7 (1.5)ac

n.d.

PPi-Far-PMs

3.7 (2.5)bcd

26.7 (1.7)bd

14.2 (1.9)bd

2.7 (1.2)bde

n.d.

  1. The Keyes’ scores are presented as the average of all the measurements (n = 7). Values followed by the same superscripts (a, b, c, d, e) are not significantly different from each other (P >0.05; comparison for all pairs using Tamhane’s T2 test)
  2. E, enamel affected; Ds, dentin exposed; Dm, 3/4 of the dentin affected; and Dx, whole dentin affected; n.d., not detectable