Fig. 8
From: Oral delivery of insulin with intelligent glucose-responsive switch for blood glucose regulation
CLSM observation of the distribution of F-actin (a), ZO-1 (b) and occludin (c) on Caco-2 cells cultured with GR-NPs 1 and GR-NPs 3; The transport permeability of FITC-INS and FITC-INS/GOx GR-NPs in fresh intestine (d), **P < 0.01: significance: comparison between FITC-INS/GOx GR-NPs and FITC-INS solution; Schematic illustration of GR-NPs overcoming epithelial barriers on intestinal cell (e)