Fig. 4

Time kinetics of PS-particle concentrations in maternal and fetal compartment using HSA- (continuous line, n = 5), IgG medium (dashed line, n = 3) or control medium (dotted grey line, n = 5). Each graph shows data obtained from different sampling ports: a maternal artery, b maternal vein, c fetal artery, and d fetal vein. Statistical analysis was performed by a linear mixed model. Significant interaction effects (time, media) are displayed above distinct time points (c). Significant main effect (media) is indicated to the right of the graphs (d). (Statistically significant differences are depicted as: *p < 0.05, **p < 0.01 and ****p < 0.0001. Data are presented as mean ± SD