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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Synergistic inhibition of metastatic breast cancer by dual-chemotherapy with excipient-free rhein/DOX nanodispersions

Fig. 3

a CLSM images of the cellular uptake of RHE, DOX, RHE/DOX and RD NPs at equivalent RHE (2.0 μM) and DOX concentrations (1.0 μM) in 4T1 cells. b Line-scanning profiles of the fluorescence intensity of 4T1 cells incubated with these preparations. c Apoptosis of 4T1 cells after an incubation with RHE, DOX, RHE/DOX and RD NPs (n = 3, mean ± SD). *p < 0.05

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