Fig. 5
In vivo IVIS imaging of αHER2/Lipo-DiR and αDNS/Lipo-DiR. The delivery of αHER2/Lipo-DiR in HER2-overexpressing tumors. a αHER2/Lipo-DiR, Lipo-DiR and αDNS/Lipo-DiR were intravenously injected in mice bearing HER2++ (right m.f.p) and HER2+/− (left m.f.p) tumors. The fluorescence intensity of DiR was detected at 24 h, 48 h and 72 h after injection by IVIS. The radiant efficiency of color bar was calculated by [p/s/cm2/sr]/[µW/cm2]. b Quantification of average radiant efficiency in HER2++ tumor and HER2+/− tumor at 24 h and 72 h