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Table 2 Quantification of AGuIX® NPs in the different fractions of MucilAir™ cultures after apical exposure to NPs at 10 mM demonstrated the fast clearance of healthy tissue

From: Multiparametric investigation of non functionalized-AGuIX nanoparticles in 3D human airway epithelium models demonstrates preferential targeting of tumor cells

Conditions

24 h

72 h

Apical fraction (%)

Basal fraction (%)

Apical fraction (%)

Basal fraction (%)

With mucus

61 ± 20

14 ± 3

0.3 ± 0.1

7 ± 1

Without mucus

59 ± 19

13 ± 1

0.1 ± 0.1

5 ± 1

  1. Gd was collected and measured by the ICP technique. The time point 72 h corresponds to 24 h exposure, followed by additional 48 h of culture. The results are presented as the percentage of the theoretical initial content
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Journal of Nanobiotechnology

ISSN: 1477-3155

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