Fig. 4

Comparison of predicted and observed experimental dose enhancement for gold nanoparticle studies. In horizontal axis, ‘Increase in physical dose’ refers to the ratio of the additional dose deposited by X-rays in the system due to the addition of GNPs to that which would be deposited in the absence of gold. Conducted energy source represented by kilovoltage (triangle) and megavoltage (black-up pointing triangle). The dashed line indicates the trend which would be followed if the sensitizer enhancement ratio directly involved with the predicted increases in physical dose. (Radiosensitization by gold NPs: effective at megavoltage energies and potential role of oxidative stress) Reproduced with permission from reference: [52], copyright 2013 Pioneer Bioscience Publishing Company