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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: pH-responsive and hyaluronic acid-functionalized metal–organic frameworks for therapy of osteoarthritis

Fig. 5

a Hematoxylin and eosin (HE) and b safranin O/fast green staining of cartilage after treatment for 4 and 8 weeks (scale bar: 500 μm). c OARSI scores for histology of articular cartilage after treatment for 4 and 8 weeks. Data were presented as the mean ± SD (n = 6). *, #p < 0.05; **, ##p < 0.01; ***, ###p < 0.001. d Immunohistochemical staining of MMP-13 in cartilage after treatment for 4 and 8 weeks (scale bar: 100 μm)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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