Fig. 16From: Recent progress in the development of upconversion nanomaterials in bioimaging and disease treatmentCopyright 2015, 2017. American Chemical Society. Reproduced with permission.)a Schematic illustration of the design of UCNP based drug delivery system for photodynamic therapy. b Plot for the potential molecular mechanism of inducing apoptosis with UCNPs@TiO2-based NIR light-mediated PDT treatment [176]. c Scheme summarizing the mechanisms of combining NIR-mediated PDT with CTLA-4 checkpoint blockade for cancer immunotherapy. UCNP-Ce6-R837 nanoparticles under NIR light would enable effective photodynamic destruction of tumors [116]. (Back to article page