Fig. 7From: Nebulised surface-active hybrid nanoparticles of voriconazole for pulmonary Aspergillosis demonstrate clathrin-mediated cellular uptake, improved antifungal efficacy and lung retentionFluorescence microscopic images of cellular uptake of Rhodamine 123 loaded lipid-polymer hybrid nanoparticles (10 µg.mL−1of R 123) depicted by Green fluorescence, Blue fluorescence-nuclei stained with DAPI, a A549 control cells, b A549 treated cells, c Calu 3 control cells, and d Calu 3 treated cells. Time-dependent uptake studies in e A549 3 cells and f Calu 3 cells. g Concentration-dependent uptake studies in A549 and Calu 3 cells. Data is expressed as mean ± SD (n = 3)Back to article page