Fig. 6

Intestinal localization of FITC-Insulin after oral administration of each formulation in mice. The dose was equivalent to 50 IU/kg FITC-Ins. a, b CLSM images of excised small intestinal epithelium with normal villi (non-PPs) (a) and intestinal Peyer’s patch (PPs) (b). White arrows indicate FITC-labeled insulin and the scale bar represents 200 μm. c Quantitation of FITC-Insulin in intestinal tissues (mean ± SD, n = 3). *p < 0.05