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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Au-siRNA@ aptamer nanocages as a high-efficiency drug and gene delivery system for targeted lung cancer therapy

Fig. 7

Histology and Immunohistochemistry of mice tissues treated with gold nanocages. a Immunohistochemical analysis of VEGF in lung tissue. ~70% reduction of VEGF expression was observed in the lungs treated with Au-siRNA-PAA-AS1411; VEGF (red chanel); Nuclei (blue chanel); b Histological analysis of lung tissue treated with Au-siRNA-PAA-AS1411(DOX) compared with the control groups of lung tissue treated with siRNA and DOX-loaded Au-siRNA-PAA; c H&E-stained tissue sections from mice subjected to inhalation-mediated local treatment with DOX-loaded Au-siRNA-PAA-AS1411 and PBS for 36 days. Scale bars: 50 µm

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Journal of Nanobiotechnology

ISSN: 1477-3155

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