Fig. 8

Effect of siEphA2 complexes co-administered with JIB-04 on the migration ability of PC-3 cells. a Representative phase-contrast images of PC-3 cells showing the changes in the scratch area in response to treatments. MRI Wound Healing Tool plugin of ImageJ was used to automatically determine the scratch area. See Additional file 1: Fig. S4 for scratch images at all time points. Scale bar: 1000 µm. b Bar plots showing the scratch area calculated at 0, 24, 48, and 72 h. Data are shown as mean ± SEM. Asterisks represent statistical significance (UT: Untreated control, ns: not significant, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, two-way ANOVA followed by Dunnett’s test; n = 3)