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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Novel controlled and targeted releasing hydrogen sulfide system exerts combinational cerebral and myocardial protection after cardiac arrest

Fig. 3

In vitro protective effects of DATS@MION-PEG-LF against hypoxia/reoxygenation induced damage in rat cardiomyocytes and neurons. Cardiomyocytes cell viability (a), lactate dehydrogenase (LDH) activity (b), flow cytometry assay (c), and apoptosis proportion (d) were evaluated after 4 h hypoxia and 1 h reoxygenation procedure; neuron cell viability (e), LDH activity (f), flow cytometry assay (g), and apoptosis proportion (h) were evaluated after same experimental protocols. Flow cytometry assay and apoptosis proportion evaluation were performed at the most protective concentration (5 µg/mL for cardiomyocytes, and 7 µg/mL for neurons). *: P < 0.05 compared with the Control (mean ± SEM, n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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