Fig. 5

In vivo effect of free drugs and NLCs on MRSA-infected mice during 40 h: a MRSA CFU in organs; b elastase distribution in organs observed by IVIS; c IFN-γ expression in organs; d IL-1β expression in organs; e IL-6 expression in organs; f IL-17A expression in organs; g TNF-α expression in organs. All data are expressed as the mean ± SEM (n = 6 for MRSA CFU and elastase analysis). * p < 0.05 as compared to MRSA-infected group. CFU, colony-forming unit; IFN-γ, interferon-γ; IL-1β, interleukin-1β; IL-6, interleukin-6; IL-17A, interleukin-17A; MRSA, methicillin-resistant Staphylococcus aureus; TNF-α, tumor necrosis factor-α