Fig. 2

Real-time mechanical response in single cells. a Initial D(t) and resulting displacement d(t) of unlabeled control cells over a 30 min period, with fit of d(t) shown in red. b Viscoelastic modulus G (0.8 Hz) of two control cells after 30 min of measurement. c Initial D(t) and resulting displacement d(t) at the starting point of the measurement and after 30 min of magnetic nanoparticle exposure, with fit of d(t) shown in red. d Viscoelastic modulus G (0.8 Hz) of two labeled cells over 45 min of measurement. Black arrows signal the time of addition of nanoparticles. Data represent mean ± SEM (n = 3 measurements of the same cell over the shown timepoint). e Magnetic nanoparticle uptake at [Fe] = 50 mM up to 30 min of incubation for F9 cells labeled while in 2D culture or in suspension. Data represent mean ± SD (n = 50 cells analyzed for each time point)