Fig. 7
From: Edible CaCO3 nanoparticles stabilized Pickering emulsion as calcium‐fortified formulation
Gastrointestinal fate of the VD3 loaded CaCO3 NPs stabilized emulsion in simulation mode. a Schematic illustration of the digestion of CaCO3 NPs stabilized Pickering emulsion in simulated gastric and intestinal fluids. b Percentage of Ca2+ generated by gastric acid hydrolysis from CaCO3 NPs. c FFA released during the simulated intestinal lipolysis over time. Data points are mean ± standard deviation of the triplicates. An asterisk indicates statistically significant (p < 0.05) differences among samples. d Percentage of remaining VD3 after gastric and intestinal (left y-axis) and the percentage of VD3 solubilized in the simulated intestinal fluid after 2-h digestion (right y-axis). Data points are mean ± standard deviation of the triplicates. An asterisk indicates statistically significant (p < 0.05) differences among samples. Visual appearance of the diluted emulsion before and after simulated gastric and intestinal phases: e TW80, f CaCO3 NPs. g Fluorescent imaging of the oily phase of the emulsion and chyme obtained after simulated gastric and intestinal phases with CaCO3 NPs. The scale bar: 400 µm