Fig 5.

Effects of Phellodendri Chinensis Cortex-based carbon dots (PCC-CDs) on appearance of the dorsal skin and right ears tissues in imiquimod (IMQ)-induced psoriasis-like mice on day 7. A–F Presentation of phenotype of animal entirety, a–f Magnification of dorsal skin and (a–f) right ear tissues. Mouse were assigned into six groups: control (Normal saline [NS], 0.5 mL), IMQ (NS,0.5 mL), methotrexate [MTX] (1.0 mg/kg), different doses of PCC-CDs groups (High[H]: 0.86 mg/kg; Medium[M]: 0.43 mg/kg; Low[L]: 0.22 mg/kg). Except for control group, IMQ and drug-treated group were received a daily application of IMQ