Fig 8.

Representative microphotographs and epidermal thickness of a, b, e dorsum skin and c, d, f right ear tissues of mouse. Animals were divided into control, model (only treated with imiquimod [IMQ]), positive (treated with methotrexate [MTX]), Phellodendri Chinensis Cortex-based carbon dots (PCC-CDs) at high[H]-(0.86 mg/kg), medium[M]-(0.43 mg/kg) and low[L] (0.22 mg/kg) doses groups (a and c H & E staining; magnification×5; b and d H & E staining; magnification×10). Data were expressed as means ± standard deviation (SD). *P < 0.05 and **P < 0.01 vs. control group,  ^#P < 0.05 and ^##P < 0.01 vs. IMQ group