Fig. 13

a Percent inhibition of amastigotes of Amp-B-MTC at various concentrations and comparison with plain thiolated nanosystem (TC), non-thiolated nanosystem (UC), AmBisome and Amphotericin B (AmB) [162]. b IC₅₀ of Amp-B-MTC against L. donovani amastigotes [162]. c Comparative cell viability assay showing safety of Amp-B-MTC [160]. d In vitro anti-leishmanial response in terms of—Inhibition (%) of mannosylated thiolated polyethylenimine nano-DDS. against L. tropica amastigotes at various concentrations [163]. e Trypanothione reductase inhibition at multiple log concentrations of designed polymers with their respective IC₅₀ [165]