Fig. 4

HGC-TAC diminished lupus-specific inflammation. a CD68 protein levels from wild-type (WT), MRL/lpr mice treated with vehicle, or MRL/lpr mice treated with an equivalent dose of TAC or HGC-TAC. b Relative protein intensities. The values for the WT vehicle-treated group are set to 1. (n = 6 mice/group). c–e Immunohistochemical staining of kidney sections for CD68, F4/80, and tumor necrosis factor-α (TNF-α) from each group. Magnification ×400, Bar = 25 μm. f Staining of CD68, F4/80, and TNF-α in the glomerulus was quantified and expressed as a percentage of positive glomerular area. Data are shown as mean ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001. ns not statistically significant