Fig. 4

PLGA NPs cause an increasing inflammatory factor release in ApoE^−/− mice on a HFD and long-term injection. a Representative images of immuno-histochemistry staining with antibodies to TNF-α, IL-6 and IL-10. b Quantitative data of TNF-α, IL-6 and IL-10 in plaque areas of the aortic root sections. n = 4, mean ± SD, *P < 0.05; **P < 0.01