Fig. 5
From: Expression and mechanism of exosome-mediated A FOXM1 related long noncoding RNA in gastric cancer
Influence of FRLnc1 overexpression on the proliferation and migration of GC cells. a the influence of FRLnc1 overexpression on the expression of FRLnc1 in MKN45 cells; b the growth of MKN-45 cells treated with FRLnc1 overexpression detected by cell growth curve; c the clone-forming ability of MKN45 cells treated with FRLnc1 overexpression detected by cell clone-forming experiment; d the mRNA expression of Cyclin D1 in FRLnc1 overexpression MKN45 cells detected by qRT-PCR; e the cell cycle of FRLnc1 overexpression MKN45 cells detected by flow cytometry; f the cell apoptotic rates of FRLnc1 overexpression MKN45 cells detected by flow cytometry; g the mRNA expressions of Bcl-2 and Bax in FRLnc1 overexpression MKN45 cells detected by qRT-PCR; h the migration ability of FRLnc1 overexpression MKN45 cells detected by Transwell migration test; i the mRNA expressions of EMT related genes in FRLnc1 overexpression MKN45 cells detected by qRT-PCR; and j the protein expressions of cyclin D1, Bcl-2 and EMT related genes in FRLnc1 overexpression MKN45 cells detected by Western blot, and the influence of FRLnc1 overexpression on ERK signaling pathways in MKN45 cells