Fig. 5

In vitro chemo/photothermal therapeutic effect of PTX@GO-PEG-OSA NSs. a Viabilities of HGC-27/PTX cells after incubation with DMEM plus 10%FBS, DMEN plus 10% PBS and NIR, GO-PEG-OSA and PTX@GO-PEG-OSA, with or without NIR irradiation. b EdU images and statistics EdU-positive number of HGC-27/PTX cells after the incubation with GO-PEG-OSA and PTX@GO-PEG-OSA, with or without NIR irradiation. Scale bar, 100 µm. c Flow cytometry images and statistics apoptotic number of HGC-27/PTX cells after the incubation with GO-PEG-OSA and PTX@GO-PEG-OSA, with or without NIR irradiation. d Expression of caspase-3, cleaved caspase-3, Bax, Bcl-2, p53 proteins and GAPDH protein in HGC-27/PTX cells after the incubation with GO-PEG-OSA and PTX@GO-PEG-OSA, with or without NIR irradiation. Data are shown as the mean ± SD, n = 3. ** indicates P < 0.01, *** indicates P < 0.001