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Table 2 Intracellular PAMAM dendrimer content at different exocytosis times in MCF-7/ADR cells

From: Effects of the surface charge of polyamidoamine dendrimers on cellular exocytosis and the exocytosis mechanism in multidrug-resistant breast cancer cells

 

0 h

3 h

6 h

9 h

12 h

PAMAM-NH2

100 ± 5.5%

75.54 ± 1.5%

55.67 ± 4.5%

35.45 ± 3.4%

33.11 ± 1.6%

PAMAM-OH

100 ± 8.5%

94.25 ± 4.1%

81.04 ± 1.1%

81.93 ± 1.6%

80.08 ± 2.9%

PAMAM-COOH

100 ± 4.9%

96.37 ± 5.4%

70.73 ± 9.5%

53.66 ± 6.8%

64.39 ± 8.1%

  1. All values are relative to the amount at 0 h. Mean ± SD, n = 3