Fig. 3From: Nanoscopic quantification of sub-mitochondrial morphology, mitophagy and mitochondrial dynamics in living cells derived from patients with mitochondrial diseasesCristae analysis of mitochondria in human-derived normal and SLC25A46 mutant fibroblasts. Normal cristae (a) were observed in human-derived normal fibroblasts, while invisible cristae and a reduced number and length of cristae (b) were observed in SLC25A46 mutant fibroblasts. Quantification analysis of cristae included the number of cristae per µm (c), cristae length (d), and cristae area (e). Data are present as mean ± SD (n = 8); **p < 0.01, *p < 0.05, as compared to normal fibroblastsBack to article page