Fig. 5
Immunofluorescence assay of Cy5.5@mPDA/MnO2/PDA NPs and Cy5.5@mPDA/MnO2/PDA-ZHer2 NPs in SKOV-3 tumor tissues. Mice bearing SKOV-3 tumors were intravenously injected with Cy5.5@mPDA/MnO2/PDA NPs or Cy5.5@mPDA/MnO2/PDA-ZHer2 NPs (100 μL; 1 mg/mL in PBS). Tumors were collected and further studied by immunofluorescence assay after 12 h post-injection. a The immunofluorescence images of Cy5.5@mPDA/MnO2/PDA NPs (red) in tumor tissues; b The immunofluorescence images of Cy5.5@mPDA/MnO2/PDA-ZHer2 NPs (red) in tumor tissues; c Representative magnified immunofluorescence images corresponding to (a) and (b). Scale bar = 100 μm. The nuclei and Her2 were stained with DAPI (blue), anti-Her2 antibody (green), respectively