Fig. 2
Tumor-binding ability of Cy5-EV-N3 and cell uptakes of Cy7-EV-N3 with different incubation time. a Fluorescence images of HCT116 cells after incubating with Cy5-EV-N3 for different time points (200 ×). b Corresponding quantification of the fluorescent intensity. c Tumor-binding ability was detected by confocal imaging (600 ×). d Uptakes of 68 Ga-L-NETA-DBCO in HCT116 tumor cells (incubated with Cy7-EV-N3 for different time periods) at the indicated time points. Bars represent means ± SD (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001