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Table 3 Hematological parameters of the mice on the 24st day

From: pH-activated, mitochondria-targeted, and redox-responsive delivery of paclitaxel nanomicelles to overcome drug resistance and suppress metastasis in lung cancer

 

PBS

P-P/ptx

P-SS-P/PTX

DA-P-SS-P/PTX

Reference Range

WBC (109/L)

8.5 ± 4.25

7.25 ± 5.25

7.36 ± 9.25

4.56 ± 0.85

0.8–6.8

Lymph (109/L)

7.85 ± 10.32

6.65 ± 1.35

6.05 ± 2.32

2.65 ± 0.35

0.7–5.7

Mon (%)

2.32 ± 0.05

1.32 ± 0.35

1.32 ± 0.23

0.25 ± 0.07

0.0 –0.3

Gran (109/L)

9.02 ± 3.52

2.32 ± 0.85

1.65 ± 0.35

0.15 ± 0.04

0.1 –1.8

RBC (1012/L)

7.35 ± 3.02

7.32 ± 2.56

7.86 ± 3.65

7.69 ± 4.52

6.36–9.42

HGB (g/l)

99.36 ± 56.23

115.6 ± 35.63

125.6 ± 45.3

120.5 ± 52.3

110–143

HCT (%)

32.5 ± 10.35

33.56 ± 10.35

41.25 ± 10.32

36.25 ± 5.65

34.6–44.6

MCV (fl.)

45.26 ± 1.25

41.35 ± 3.25

41.24 ± 1.32

40.56 ± 1.85

48.2–58.3

MCH (pg)

13.2 ± 3.25

16.52 ± 3.25

17.25 ± 2.85

17.56 ± 3.14

15.8–19

MCHC (g/l)

301.1 ± 85.54

322.5 ± 102.5

345.8 ± 112.3

335.6 ± 132.5

302–353

RDW (%)

16.35 ± 3.12

18.52 ± 3.02

15.35 ± 2.32

16.35 ± 4.56

13–17

MPV (fl.)

6.23 ± 0.23

6.10 ± 0.15

5.85 ± 0.65

5.45 ± 0.85

3.8 –6.0