Fig. 5

A Intracellular uptake of PLNE and PLNE-PTX was visualized by confocal microscopy (scare bar = 20 µm). B The cellular uptake of PLNE and PLNE-PTX was quantified (n = 3 per group) by flow cytometry. C In vitro therapeutic efficacy was deteremined using an alamarBlue assay. KB cells were treated with either: (1) PLNE, (2) monotherapy Taxol, (3) PLNE-PTX single chemotherapy, (4) PLNE + laser irradiation for monotherapy PDT, and (5) PLNE-PTX + laser irradiation for combination therapy. %) (*** represents p < 0.001 by two-way ANOVA test; n = 6 per group)