Table 1 Formulation of PLNEnoPEG, PLNE, and 0.4–1.6 mg PTX-PLNE
PLNEnoPEG | PLNE | 0.4 mg PLNE-PTX | 0.8 mg PLNE-PTX | 1.2 mg PLNE-PTX | 1.6 mg PLNE-PTX | |
|---|---|---|---|---|---|---|
Porphyrin-lipid | 4.1 mg (4 µmol) | |||||
DSPE-PEG 2000 | n/a | 0.58 mg (0.2 µmol) | ||||
Glyceryl trioctanoate | 19.2 mg (40.8 µmol) | |||||
Paclitaxel | n/a | 0.4 mg (0.5 µmol) | 0.8 mg (0.9 µmol) | 1.2 mg (1.4 µmol) | 1.6 mg (1.9 µmol) | |