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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Promising PEGylated cationic dendrimers for delivery of miRNAs as a possible therapy against HIV-1 infection

Fig. 2

Genotoxicity of carbosilane cationic dendrimers. Quantification of the number of sister-chromatid exchange per cell in PBMCs non-treated, PBMCs treated with G2-SN15-PEG 10 µM, G3-SN31-PEG 5 µM or 1 Gy of radiation for 72 h. a Images of random field obtained from the SCE assay after FPG staining. Arrows indicated the sister-chromatid exchange. b Analysis of the SCE assay. Data are represented as dot plots of five individual experiments (50 mitosis analysis per healthy donor). C + 1 Gy 1 Gy radiation control, NT non-treated. (*p < 0.05; **p < 0.01; ***p < 0.001)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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