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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Promising PEGylated cationic dendrimers for delivery of miRNAs as a possible therapy against HIV-1 infection

Fig. 3

Dendriplexes characterization. a Two per cent agarose gel electrophoresis showing the formation of different dendriplexes after 2 h, 24 h or 48 h of incubation of control microRNA with G2-SN15-PEG 10 µM and G3-SN31-PEG 5 µM dendrimers. b Percentage of microRNA captured vs. miRNA control after 2, 24 or 48 h of incubation. c Formation of dendriplexes with anti-HIV-1 microRNAs (hsa-miR-29a-3p, hsa-miR-29b-3p, hsa-miR-92a-3p, hsa-miR-133b and hsa-miR-149-5p) and G2-SN15-PEG (10 µM) and G3-SN31-PEG (5 µM) dendrimers after 2 h of incubation. d Percentage of microRNA captured vs. miRNA control after 2 h of incubation. e Formation of dendriplexes with anti-HIV-1 microRNAs and G2-SN15-PEG (5 µM) and G3-SN31-PEG (1 µM) dendrimers. f Percentage of microRNA captured vs. miRNA control

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