Table 4 Sequence, HIV-1 target and effect on HIV-1 replication of selected anti-HIV-1 microRNAs and control microRNA
Name | Sequence | HIV-1 genome target | Effect on HIV-1 replication |
|---|---|---|---|
miR-29a-3p | UAGCACCAUCUGAAAUCGGUUA | Nef/3’UTR | Negative |
miR-29b-3p | UAGCACCAUUUGAAAUCAGUGUU | Nef/3’UTR | Negative |
miR-92a-3p | UAUUGCACUUGUCCCGGCCUGU | Pol | Negative |
miR-133b | UUUGGUCCCCUUCAACCAGCUA | Env | Negative |
miR-149-5p | UCUGGCUCCGUGUCUUCACUCCC | Gag | Negative |
miR-Control | UCACCGGGUGUAAAUCAGCUUG | - | None |