Fig. 7

Theoretical sensitivity of the capacitance gradient to variations of the specific capacitance of the lipid bilayer membrane, c_m, as a function of the specific capacitance for measurements performed on a uni-lamellar liposome with height h = 100 nm, diameter D = 500 nm and internal conductivities σ_lip = 0.001 S/m and 1 S/m (black continuous lines). The red dashed line corresponds to the case of a solid supported planar lipid bilayer patch of diameter D_m = 500 nm and thickness h_m = 5 nm. Parameters of the calculations: σ_sol = 0.2 S/m, ε_sol = ε_lip = 78, R = 30 nm, θ = 20°, f_el = 5 MHz, z = 50 nm. Inset: schematic representation of the two systems considered