Fig. 6
A Prussian blue iron staining of tumor specimens. (a, USPIO-PEG group, and there was a small amount of iron particles in the tumor tissue. b, USPIO-PEG-sLex group, and the blue reaction products were diffuse in the tumor.) B Prussian blue iron staining of different tissues. In A and B, The blue particles were iron particles and the red backgroud were tumor tissue (A) and normal organ tissue (B) (a, c, e, g, and i are liver, spleen, heart, kidney and muscle of nude mice in the USPIO-PEG group, respectively. And b, d, f, h, and j are liver, spleen, heart, kidney and muscle of nude mice in the USPIO-PEG-sLex group). C IHC staining. The brown area was the antigen–antibody reaction product, and the blue area was the nucleus. The expression of E-selectin was low positive in the both group (a, USPIO-PEG group and b, USPIO-PEG-sLex group). And it could be seen both cytoplasm and membrane