Fig. 2

Drug release and IDO inhibition efficiency. a, b Drug release kinetics, tested with PPF NPs in buffer solutions with pH 5.5 and 7.4 in the presence and absence of photo-irradiation (IR). a NLG919 release profiles. b ZnF₁₆Pc release profiles. c IDO inhibition, examined by measuring Kyn released from HeLa cells. Hela cells were first treated with IFN-γ along with either free NLG919 or PPF NPs. Kyn in the supernatant was quantified 48 h later, and compared to PBS-treated cells. The experiments were conducted in triplicate. Values are presented as means ± SD