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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Ex vivo and in vivo fluorescence detection and imaging of adenosine triphosphate

Fig. 6

Imaging and sensing ATP in real complex samples. a Schematic diagram of TC/Apt fluorescent probes for detecting ATP concentration in real complex samples, such as mouse serum, mouse urine, and human serum. b–d Corresponding histogram of fluorescence intensity of TC/Apt probes in PBS, mouse serum (b), mouse urine (c) and human serum (d) with various final concentration of the adding ATP. *** means p < 0.001. e Schematic illustrating TC/Apt probes for in vivo imaging and monitoring of tumour tissues in a mouse model. f In vivo imaging of normal site and 4T1 tumor tissues after treatment with 100 μL TC/Apt of a concentration at 200 μg/mL for 6 h. g Corresponding histograms of fluorescence intensity on the left and right back of the 4T1 tumor-bearing mice. ** means p < 0.01. h In vivo imaging of normal site and MCF-7 tumor tissues after treatment with TC/Apt of a concentration at 200 μg/mL for 6 h. i Corresponding histograms of fluorescence intensity on the left and right back of the MCF-7 tumor-bearing mice. ** means p < 0.01

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