Fig. 1
From: pH-sensitive dual drug loaded janus nanoparticles by oral delivery for multimodal analgesia
Characterization and cumulative in vitro release profiles of Janus nanoparticles. TEM image showing the structure transformation of αCT/Res-JNP under different volume ratio of surfactant to W1/O emulsion: A Core–shell structure (Surfactant: W1/O emulsion = 1:4), B Dumbbell-shaped with asymmetric attached nodes (Surfactant: W1/O emulsion = 5:12); C XRD spectra of (a) αCT, (b) Res, (c) PLGA:LWMC:ALG mixture (1:1:1), (d) αCT:Res:PLGA:LWMC:ALG mixture (1:1:1:1:1), (e) αCT/Res-JNP. D Cumulative in vitro αCT and Res release profiles of JNP in SGF (pH 1.2) and PBS (pH 7.4) (n = 3, mean ± SD)