Fig. 5
From: pH-sensitive dual drug loaded janus nanoparticles by oral delivery for multimodal analgesia
Cellular uptake of FITC-αCT by Caco-2 cells (A) and HT29/MTX cells (B) were observed by confocal laser scanning microscope. Green signal showed internalized FITC-αCT, and blue signal showed nucleus. C Cumulative trans-monolayer transport of JNP in Caco-2, Caco-2/HT29-MTX, and Caco-2/HT29-MTX/Raji monolayers (n = 3, **: FITC-αCT vs. FITC-αCT/Res-JNP, p < 0.01; *: FITC-αCT vs. FITC-αCT/Res-JNP, p < 0.05; #: Rea vs. αCT/Res-JNPs, p < 0.05)