Fig. 12
Effects of NPs on new bone formation. a Representative images of the right tibial regions from different groups. b The distance between the double fluorescence labeled lines (n = 3). Treatment groups TG1: OVX, TG2: PEG-PLGA-AL@Fe3O4 NPs, TG3: PEG-PLGA-AL@Fe3O4 NPs, TG4: PEG-PLGA-AL@Fe3O4/E2 NPs, TG5: PEG-PLGA-AL@Fe3O4/ E2 NPs + MF. *P < 0.05 versus Sham; #P < 0.05 versus PEG-PLGA-AL@E2 NPs; △P < 0.05 versus PEG-PLGA-AL@Fe3O4/E2 NPs