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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Tetraspanins are unevenly distributed across single extracellular vesicles and bias sensitivity to multiplexed cancer biomarkers

Fig. 3

Fluorescence profiling of tetraspanin expression for isolated SK-OV-3 EVs. a Representative example of tetraspanin colocalization for SK-OV-3 EVs isolated by UC after 1 week of cell growth in a bioreactor flask. b Tetraspanin colocalization pattern of SK-OV-3 EVs remained relatively consistent across 6 consecutive weeks of isolation by UC from bioreactor grown cells. Tetraspanin colocalization pattern of SK-OV-3 EVs from week 6 of the bioreactor isolated by (c) UC or (d) SEC showed some differences but did not have variation outside that seen from week to week of the bioreactor isolations. N = 3 capture spots. Error bars represent ± one s.d

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