Fig. 5
A The in vivo imaging of SK-BR-3 tumor bearing mice after intravenous injection of free Dir, Dir loaded GTSL, and GTSL-HER2. (Red circles represent the tumor site). B The images of ex vivo organ of mice at 24 h after injection free Dir, Dir loaded GTSL, and GTSL-HER2. C The average fluorescence intensity of ex vivo organs and tumors of mice at 24 h after injection of different groups (n = 3, mean ± SD). (*p < 0.05, ***p < 0.001). D In vivo photothermal imaging with a NIR laser at 0, 1, 3 and 5 min of SK-BR-3 tumor-bearing mice 24 h after intravenous injection of saline, GTSL and GTSL-HER2. (Green circles represent the tumor site). E Temperature changes of the SK-BR-3 tumor-bearing mice during NIR irradiation at different points of different groups (n = 3, mean ± SD). (**p < 0.01). F The in vivo CT imaging of SK-BR-3 tumor bearing mice after intravenous injection of PBS, Iohexol, GTSL, and GTSL-HER2. (Red circles represent the tumor site). G The average Au amount of ex vivo organs and tumors of mice at 8 h After injection of different groups (n = 3, mean ± SD). (**p < 0.01)