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Table 2 synergism in combination studies analyzed with the combination index method

From: “Petal-like” size-tunable gold wrapped immunoliposome to enhance tumor deep penetration for multimodal guided two-step strategy

Range of combination index

Description

 < 0.1

Very strong synergism

0.1–0.3

Strong synergism

0.3–0.7

Synergism

0.7–0.85

Moderate synergism

0.85–0.90

Slight synergism

0.90–1.10

Nearly additive

1.10–1.20

Slight antagonism

1.20–1.45

Moderate antagonism

1.45–3.3

Antagonism