Fig. 5
From: Mithramycin delivery systems to develop effective therapies in sarcomas
Effect of free and nanocarrier delivered MTM on cell invasion. A–B 3D spheroid invasion assays in T-5 H-FC#1 cells treated for 24 h with either DMSO (vehicle) or the indicated concentrations of the different MTM formulations. Representative images of spheroids at initial (t = 0) and final time (t = 24 h) (A) for the different treatments and the quantification of the invasive area at the indicated times (B) are displayed. Scale bars = 200 m. Data (mean and standard deviation) are calculated from at least 6 spheroids per condition and time point and expressed relative to DMSO-treated cells