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Table 1 Targeting efficacy of conventional Au-based NPs by inductively coupled plasma mass spectrometer (ICP-MS)

From: Development of theranostic dual-layered Au-liposome for effective tumor targeting and photothermal therapy

Particle name (commercial or by the authors)

Concentration of Au administered in vivo

Concentration of Au in tumor

Targeting (%ID/g)

Injection method

Refs

ELP-Au NPs

180 μg Au mL−1

0.15–0.18 μg mm−3

> 90 (after 1 day from injection)

34 (after 30 days from injection)

Intratumoral

[58]

GNPs

186 μg Au mL−1

~ 0.186 μg mm−3

~ 100 (right after injection) (this value was calculated from concentration of Au in tumor)

Intratumoral

[43]

sAuNR-laden-macrophages

2.1 μg Au μL−1

~ 0.525 μg mm−3

~ 100 (right after injection) (this value was calculated from concentration of Au in tumor)

Intratumoral

[47]

Bare AuNSs

3 mg mL−1

0.07245 μg mm−3

1.61 (after 48 h from injection)

Intravenous

[52]

MPCM-AuNSs

ND.

ND

7.48 (after 48 h from injection)

Intravenous

[52]

CPGAa

10.4 mg Au kg−1 (ND. of administrated volume)

~ 0.0147 μg mm−3

7.06 ± 0.49 (after 24 h from injection)

Intravenous

[56]

Au NPs

2 mg mL−1 (10 mg kg−1)

~ 0.02 μg mm−3 (after 12 h from injection)

1 (after 2 h from injection)

6 (after 12 h from injection)

2 (after 24 h from injection)

Intravenous

[54]

AuNP@peptide

ND

ND

3 (after 2 h from injection)

9 (after 12 h from injection)

7 (after 24 h from injection)

Intravenous

[54]

  1. ELP-Au NPs elastin-like polypeptide (ELP) conjugated Au NPs, GNPs gold nanoparticle, sAuNR 7 nm diameter Au nanorods, AuNSs gold nanoshells, MPCM-AuNS macrophage cell membrane (MPCM)-camouflaged AuNS, ND.No data
  2. aCPGA: near-infrared dye (Cy5.5) labeled-matrix metalloproteinase-14 (MMP-14) substrate (CP) was conjugated onto the GO/Au complex (GA) forming tumor targeted theranostic probe