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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Donut-like MOFs of copper/nicotinic acid and composite hydrogels with superior bioactivity for rh-bFGF delivering and skin wound healing

Fig. 6

Cell attachment and spreading behavior, migration and tubule formation activities Cellular merged fluorescent images of HUVEC (a) and NIH/3T3 cells (b) on GelMA, CuNA@GelMA and CuNA-bFGF@GelMA hydrogels after 2 days post-seeding. F-actin (red), vinculin (green), nuclei (blue). c The migration evaluation of different ionic extraction on HUVEC and NIH/3T3 cells after incubation for 24 h by the transwell method. d The tube formation of HUVEC on matrigel after incubation with ionic extraction for 4 h. The migration number of HUVEC (e) and NIH/3T3 cells (f) compared to the control group. g The relative tube formation of HUVEC cultured in different ionic extraction. Data are expressed as mean ± SD (n = 3). (*p < 0.05, **<0.01, **<0.001 compared to the control)

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