Fig. 2

Exo-181b inhibited the inflammatory response by enhancing M2 polarization macrophages in vitro. a The concentrations of TNF-α, IL-6, IL-10 of the supernatants detected by ELISA. b The relative gene expression of CCR7, CD206, Arg-1 and iNOS of RAW264.7 was detected via qRT-PCR. c, d Representative images of the percentage of CCR7 and CD206 positive cells verified by flow cytometry analysis. e, f The quantitative flow cytometry analysis of the percentage of CCR7 and CD206 positive cells. (*p < 0.05). TNF-α tumor necrosis factor-α, IL-6 interleukin-6, IL-10 interleukin-10, ELISA enzyme-linked immunosorbent assay, Arg-1 Arginase-1, iNOS inducible nitric-oxide synthase, CCR7 Cxc Chemokine Receptor 7