Fig. 4

PT + H + Exo-181b promoted osteointegration in vivo detected by MicroCT. a Representative sagittal images and 3D reconstruction of bone defects after 12 weeks treated with Ti, Ti-H, Ti-H-Exo-NC and PT + H + Exo-181b scaffolds via MicroCT analysis. Red and green represent porous titanium alloy and new-formed bone b Statistical analysis of BV/TV and BMD by the acquired MicroCT data for each group after 12 weeks. (*p < 0.05). BV bone volume, TV total volume, BMD bone mineral density